Mechanisms underlying vascular regeneration in damaged aerial organs

The article by Radhakrishnan et. al. (https://dev.biologists.org/content/147/6/dev185710) is featured in Development issue 147 (6) and is selected as one of the Research Highlights, where it shows that PLT-CUC2 regulatory module acts in a coherent feed-foreword loop to increase the local auxin production in response to injury. This instructs polarization and fate specification guiding the regenerating vein to its destination.

Journal cover features artistic rearrangement of leaf confocal micrographs displaying battery of fluorescently tagged cell fate determinants in response to injuries. Images created by Anju P. S., Dhanya Radhakrishnan and Abdul Kareem V. K. Artwork by Mabel Maria Mathew.