Dr Reji Varghese
Associate Professor (Chemistry)
+91 (0)471 - 2778074
cmVqaUBpaXNlcnR2bS5hYy5pbg==
48. Multifunctional siRNA/ferrocene/cyclodextrin nanoparticles for enhanced chemodynamic cancer therapy
Gowtham Raj, D. S. Vasudev, Sarah Christopher, Anupama Babulal, P. Harsha, Soumakanya Ram, Mehul Tiwari, Markus Sauer and Reji Varghese
Nanoscale, 2024, 16, 3755
47. Antisense DNA loaded 2D nanosheets for combined photodynamic and antisense cancer therapy
Gowtham Raj, Vasudev D. S, Justin Prasad, Erai Anbu, Soumakanya Ram, Geoffrey Bellson Daniel, Nikhil Dev Narendradev, Srinivasa Murty Srinivasula and Reji Varghese
Mater. Chem. Front., 2024, 8, 553
46. Adamantoid Scaffolds for Multiple Cargo Loading and Cellular Delivery as β-Cyclodextrin Inclusion Complexes
Arthi Ravi, Atchutarao Pathigoolla, Haripriya Balan, Ria Gupta, Gowtham Raj, Reji Varghese, and Kana M. Sureshan
Angew. Chem.Int. Ed.2023,62, e20230732
45.19F NMR ON/OFF nanoparticles: a universal approach for the specific detection of DNA-binding cancer biomarkers
Devanathan Perumal, Jithu Krishna, Kaloor S Harikrishnan, Gowtham Raj, Jemshiya Kalathil, Minu Saji, M Kavyasree, Reji Varghese
Nanoscale, 2023, 15, 8972
44. Tumor microenvironment responsive nanocarriers for efficient antisense DNA delivery and enhanced chemodynamic therapy
Gowtham Raj, DS Vasudev, Nikhil Dev Narendradev, Viswa Kalyan Kumar Dommeti, Saurabh Shriwas, PM Ajay Sekhar
Leah Susan Jacob, S Murty Srinivasula, Reji Varghese
Mater. Chem. Front., 2023, 7, 1821
.gif)
43. Supramolecular grafting of stimuli-responsive, carrier-free, self-deliverable nanoparticles of camptothecin and antisense DNA for
combination cancer therapy
Devanathan Perumal, Jemshiya Kalathil, Jithu Krishna, Gowtham Raj, Kaloor S Harikrishnan, ML Uthpala, Ria Gupta, Reji Varghese
New J. Chem., 2022, 46, 16813
42. G4-Quartet hydrogel loaded with doxorubicin and hemin for cascade chemodynamic therapy
Gowtham Raj, Viswa Kalyan Kumar Dommeti, Vinayak Pradeep, Abhindev Kizhakke Veetil and Reji Varghese
Mater. Chem. Front., 2022, 6, 1533
41. Galactose-Grafted a Scaffold for the In Situ Synthesis of Silver Nanoparticles A Potential Catalyst for the Reductionof Nitroaromatics
Kaloor S Harikrishnan, Nithiyanandan Krishnan, Nilima Manoj Kumar, Anusree Krishna, Gowtham Raj, Devanathan Perumal,
Jemshiya Kalathil, Jithu Krishna, Reji Varghese
Chem.Eur.J.2021,27, 14100–14107
40. Blue-emissive two-component supergelator with aggregation-induced enhanced emission
Swathi Vanaja Chandrasekharan, Nithiyanandan Krishnan, Siriki Atchimnaidu, Gowtham Raj, Anusree Krishna PK, Soumya Sagar,
Suresh Das, Reji Varghese
RSC Adv., 2021, 11, 19856
39. Biotin-decorated NIR-absorbing nanosheets for targeted photodynamic cancer therapy
Devanathan Perumal, Murali Golla, Kavya S Pillai, Gowtham Raj, Anusree Krishna PK, Reji Varghese
Org. Biomol. Chem., 2021, 19, 2804
38. DNA−π Amphiphiles: A Unique Building Block for the Crafting of DNA-Decorated Unilamellar Nanostructures
Shine K Albert, Murali Golla, Nthiyanandan Krishnan, Devanathan Perumal, Reji Varghese
Acc. Chem. Res. 2020, 53, 11, 2668–2679
37. Efficient Capturing of Polycyclic Aromatic Micropollutants From Water Using Physically Crosslinked DNA Nanoparticles
Siriki Atchimnaidu, Hari Veera Prasad Thelu, Devanathan Perumal, Kaloor S Harikrishnan, Reji Varghese
Frontiers in Chemistry
36. Galactose-Grafted 2D Nanosheets from the Self-Assembly of Amphiphilic Janus Dendrimers for the Capture and Agglutination of Escherichia coli
Nithiyanandan Krishnan, Devanathan Perumal, Siriki Atchimnaidu, Kaloor S. Harikrishnan, Murali Golla, Nilima Manoj Kumar, Jemshiya Kalathil, Jithu Krishna, Dileep K. Vijayan and Reji Varghese* Chem.Eur.J.2020,26,1037 –1041
35. Phototheranostic DNA micelles from the self-assembly of DNA-BODIPY amphiphiles for the thermal ablation of cancer cells
Siriki Atchimnaidu, Devanathan Perumal, Kaloor S. Harikrishanan, Hari Veera Prasad Thelu and Reji Varghese *
Nanoscale. 2020, DOI: 10.1039/d0nr02622k
34. Self-Assembly of an Aptamer-Decorated, DNA−Protein Hybrid Nanogel: A Biocompatible Nanocarrier for Targeted Cancer Therapy
Hari Veera Prasad Thelu, Siriki Atchimnaidu, Devanathan Perumal, Kaloor S. Harikrishnan, Shajesh Vijayan, and Reji Varghese*
ACS Appl. Bio Mater. 2019, DOI: 10.1021/acsabm.9b00323
33. DNA-Decorated Helically Twisted Nanoribbon: A Scaffold for the Fabrication of One-Dimensional Chiral Plasmonic Nanostructures
Murali Golla, Shine K. Albert, Devanathan Perumal, Siriki Atchimnaidu, Nithiyanandan Krishnan and Reji Varghese*
Angew. Chem. Int. Ed., 2019, 58, 3865–3869
32. Self-assembly of tetraphenylethylene based dendron into blue fluorescent nanoparticles with aggregation induced enhanced emission
Nithiyanandan Krishnan, Hanna Ameena M. A., Siriki Atchimnaidu, Devanathan Perumal, Murali Golla, Jithu Krishna and Reji Varghese*
J. Chem. Sci., 2018, (accepted) (invited article)
31. Aptamer Decorated DNAsome for Targeted Cancer Therapy
Murali Golla, Sai Praveen Thadi, Devanathan Perumal, Siriki Atchimnaidu,and Reji Varghese*
ChemNanoMat, 2018, DOI: 10.1002/cnma.201800297
30. Self-assembly of DNA-tetraphenylethylene amphiphile into DNA-grafted nanosheet as a support for the immobilization of gold nanoparticles: A recyclable catalyst with enhanced activity
Nithiyanandan Krishnan, Murali Golla, Hari Veera Prasad Thelu, Shine K. Albert, Siriki Atchimnaidu, Devanathan Perumal and Reji Varghese*
Nanoscale, 2018, DOI: 10.1039/C8NR03746A
29. Size controllable DNA nanogels from the self-assembly of DNA nanostructures through multivalent host–guest interactions
Hari Veera Prasad Thelu, Shine K. Albert, Murali Golla, Nithiyanandan Krishnan, Divya Ram, S. Murty Srinivasula and Reji Varghese*
Nanoscale, 2018, 10, 222–230
28. DNA-Decorated Two-Dimensional Crystalline Nanosheets
Shine K. Albert, Irla Sivakumar, Murali Golla, Hari Veera Prasad Thelu, Nithiyanandan Krishnan, Joseph Libin K. L., Ashish, and Reji Varghese*
J. Am. Chem. Soc.2017, 139, 17799–17802
27. A pH-responsive DNAsome from the self-assembly of DNA-phenyleneethynylene hybrid amphiphile
Shine K. Albert, Hari Veera Prasad Thelu, Murali Golla, Nithiyanandan Krishnan, Reji Varghese*
Chem. Eur. J. 2017,23, 8348–8352
26. Modular Synthesis of Supramolecular DNA Amphiphiles through Host-guest Interactions and their Self-assembly into DNA-decorated Nanovesicles
Shine K. Albert, Hari Veera Prasad Thelu, Murali Golla, Nithiyanandan Krishnan, Reji Varghese*
Nanoscale 2017, 9, 5425-5432.
25. DNA-Decorated Luminescent Vesicles as Drug Carriers
Hari Veera Prasad Thelu, Shine K. Albert, Murali Golla, Nithiyanandan Krishnan, Santosh Bhargav Yamijala, Sreeja V. Nair, S. Murty Srinivasula,* Reji Varghese*
ChemistrySelect 2016, 1, 5389 – 5396. (DOI: 10.1002/slct.201600897)
24. Synthesis and self-assembly of DNA–chromophore hybrid amphiphiles
Shine K. Albert, Murali Golla, Hari Veera Prasad Thelu, Nithiyanandan Krishnan, Perapaka Deepak and Reji Varghese*
Org. Biomol. Chem. 2016, 14, 6960. (DOI: 10.1039/c6ob00681g)
23. DNA-Based Oligochromophores as Light-Harvesting Systems?
P. Ensslen, F. Brandl, S. Sezi, R. Varghese, R.-J. Kutta, B. Dick, H.-A. Wagenknecht*
Chem. Eur. J. 2015, 21, 9349. 
22. Self-Assembly of DNA–Oligo(p-phenylene-ethynylene) Hybrid Amphiphiles into Surface-Engineered Vesicles with Enhanced Emission
Shine K. Albert, Hari Veera Prasad Thelu, Murali Golla, Nithiyanandan Krishnan, Soma Chaudhary, and Reji Varghese*
Angew. Chem. Int. Ed. 2014, 53, 8352-8357. (DOI: 10.1002/anie.201403455)
21. Conformational Control of Dual Emission by Pyrrolidinyl PNA-DNA Hybrids
S. Sezi, R. Varghese, T. Vilaivan, H.-A.Wagenknecht*
ChemistryOpen2012, 1, 173.
20. Oligo(p-phenyleneethynylene)Derived Super -Gelators with TunableEmission and Self-assembled Polymorphic Structures
Anesh Gopal, Dr. Reji Varghese and Ayyappanpillai Ajayaghosh*
Chem. Asian J. 2012, 7, 1963. (DOI: 10.1002/asia.201290035)(coverpage)
19. Site-specific synthesis and in situ immobilization of fluorescent silver nanoclusters on DNAnanoscaffolds by use of the Tollens reaction
S. Pal, R. Varghese, Z. Deng, Z. Zhao, A.Kumar, Y. Liu,* H. Yan*
Angew. Chem. Int. Ed. 2011, 50, 4176. (DOI: 10.1002/anie.201007529)
18. DNA directed artificial light harvesting antenna
P. K. Dutta, R. Varghese, J.Nangreave, S. Lin, H. Yan,* Y. Liu*
J. Am. Chem. Soc. 2011, 133, 11985-11993. (DOI: 10.1021/ja1115138)
17. Non-covalent versus Covalent Control of Self-assembly and Chirality of Nile Red-modified Nucleoside and DNA
R. Varghese, H.-A. Wagenknecht*
Chem. Eur. J. 2010, 16, 9040 – 9046. (DOI: 10.1002/chem.201001136)
16. Red-White-Blue Emission Switching Molecular Beacons: Ratiometric Multicolour DNA Hybridization Probes
R. Varghese, H.-A. Wagenknecht*
Org. Biomol. Chem. 2010, 3, 526. (DOI: 10.1039/b918381g)
15. White-Light-Emitting DNA (WED)
R. Varghese, H.-A. Wagenknecht*,
Chem. Eur. J. 2009, 15, 9307 (with cover page), (DOI: 10.1002/chem.200990142)
14. Synthesis and Optical Properties of Nile Red Modified 2?-Deoxyuridine and 7-Deaza-2?-deoxyadenosine: Highly Emissive Solvatochromic Nucleoside
R. Varghese, P. K. Gajula, T. K. Chakraborty, H.-A. Wagenknecht*
Synlett 2009, 3252. (DOI: 10.1055/s-0029-1218384)
13. DNA as a supramolecular framework for the helical arrangements of chromophores: towards photoactive DNA-based nanomaterials
R. Varghese, H.-A. Wagenknecht*
Chem. Commun. 2009, 19, 2615. (DOI: 10.1039/B821728A) (Feature Article)
12. Helical Supramolecular Architectures of Self-Assembled Linear ?-Systems
V. K. Praveen, S.S. Babu, C. Vijayakumar, R. Varghese, A. Ajayaghosh*
Bull. Chem. Soc. Jpn. 2008, 81, 1196. (DOI: http://dx.doi.org/10.1246/bcsj.81.1196)
11. Solvent Induced Aggregation and Cation Controlled Self-assembly of Tripodal Squaraine Dyes: Optical, Chiroptical and Morphological Properties
P. Chithra, R. Varghese, K. P. Divya, A. Ajayaghosh*
Chem. Asian J. 2008, 3, 1365. (DOI: 10.1002/asia.200800133)
10. Controlled self-assembly of squaraines to 1D supramolecular architectures with high molar absorptivity
A. Ajayaghosh*, P. Chithra, R. Varghese, K. P. Divya
Chem. Commun. 2008, 969. (DOI: 10.1039/b718054c)
9. Quadrupolar ?-Gels: Sol-Gel Tunable Red-Green-Blue (RGB) Emission in Donor-Acceptor Type Oligo(p-phenylenevinylene)s,
A. Ajayaghosh* V. K. Praveen, S. Srinivasan, R. Varghese
Adv. Mater. 2006, 19, 411. (DOI: 10.1002/adma.200601500)
8. Self-Assembly of Tripodal Squaraines: Cation Assisted Expression of Molecular Chirality and Spherical to Helical Morphology Change
A. Ajayaghosh*, P. Chithra, R. Varghese
Angew. Chem. Int. Ed. 2006, 45, 230. (DOI: 10.1002/anie.200603611)
7. Vesicles to Helical Nanotubes: An Unprecedented “Sergeant and Soldiers” Effect in the Selfassembly of Oligo(p-phenyleneethynylene)s
A. Ajayaghosh*, R. Varghese, S. Mahesh, V. K. Praveen
Angew. Chem. Int. Ed. 2006, 45, 7729. (DOI: 10.1002/anie.200603238)
6. Self-Assembled ?-Nanotapes as Donor Scaffolds for Selective and Thermally Gated Fluorescence Resonance Energy Transfer (FRET)
V. K. Praveen, S. J. George, R. Varghese, C. Vijayakumar, A. Ajayaghosh*
J. Am. Chem. Soc. 2006, 128, 7542. (DOI: 10.1021/ja0587594)
5. Self-Location of Acceptors as “Isolated” or “Stacked” Energy Traps in a Supramolecular Donor Self-Assembly:
A Strategy to Wavelength Tunable FRET Emission
A. Ajayaghosh*, C. Vijayakumar, V. K. Praveen, S. S. Babu, R. Varghese
J. Am. Chem. Soc. 2006, 128, 7174. (DOI: 10.1021/ja0621905)
4. Evolution of Nano- to Microsized Spherical Assemblies of a Short Oligo(p-phenyleneethynylene) into Superstructured Organogels
A. Ajayaghosh*, R. Varghese, V. K. Praveen, S. Mahesh
Angew. Chem. Int. Ed. 2006, 45, 3261. (DOI: 10.1002/anie.200600256)
3. Transcription and Amplification of Molecular Chirality to Oppositely Biased Supramolecular ?-Helices
A. Ajayaghosh*, R. Varghese, S. J. George, C. Vijayakumar
Angew. Chem. Int. Ed. 2006, 45, 1141. (VIP with cover picture; DOI: 10.1002/anie.201201268)
2. Cholesterol-Aided Supramolecular Control over Chromophore Packing: Twisted and Coiled Helices with Distinct Optical, Chiroptical and Morphological Properties
A. Ajayaghosh*, C. Vijayakumar, R. Varghese, S. J. George
Angew. Chem. Int. Ed. 2006, 45, 456. (VIP) (DOI: 10.1002/anie.200503258)
1. Anion Induced Modulation of Self-Assembly and Optical Properties in Urea Endcapped Oligo(p-phenylenevinylene)s
R. Varghese, S.J. George, A. Ajayaghosh*
Chem. Commun. 2005, 593. (DOI: 10.1039/B413909G)
