Dr Poonam Thakur
Assistant Professor Grade I (Biology)
  +91 (0)471 - 2778254
  poonam@iisertvm.ac.in

Key Publications 

1. Thakur P*, Luk K, Roeper J. Selective K-ATP channel-dependent loss of pacemaking in vulnerable nigrostriatal dopamine neurons by α-synuclein aggregates. bioRxiv, 11, 2019. https://www.biorxiv.org/content/10.1101/842344v1 . *Corresponding author

2. Thakur P, Chiu WH, Roeper J, Goldberg JA.  a-Synuclein 2.0 – Moving towards cell-type specific pathophysiology. Neuroscience- Forefront Review (2019),412:248-256. https://doi.org/10.1016/j.neuroscience.2019.06.005

3Thakur P*, Breger L*, Lundblad M, Wan OW, Mattsson B, Luk K, Lee VM, Trojanowski J, Björklund A. Modeling Parkinson’s disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain. Proceedings of the National Academy of Sciences-PNAS (2017), 114(39): E8284–E8293. https://doi.org/10.1073/pnas.1710442114. * Equal contribution

4. Thakur P and Nehru B. Inhibition of neuroinflammation and mitochondrial dysfunctions by carbenoxolone in the rotenone model of Parkinson’s disease. Molecular Neurobiology (2015), 51(1):209-219. https://doi.org/10.1007/s12035-014-8769-7

5. Thakur P and Nehru B. Long-term heat shock proteins (HSPs) induction by carbenoxolone improves hallmark features of Parkinson’s disease in a rotenone-based model. Neuropharmacology (2014), 79:190-200. https://doi.org/10.1016/j.neuropharm.2013.11.016

6Thakur P and Nehru B. Modulatory effects of sodium salicylate on the factors affecting protein aggregation during rotenone induced Parkinson’s disease pathology. Neurochemistry International (2014), 75:1-10. https://doi.org/10.1016/j.neuint.2014.05.002

7. Thakur P and Nehru B. Anti-inflammatory properties rather than anti-oxidant capability is the major mechanism of neuroprotection by sodium salicylate in a chronic rotenone model of Parkinson’s disease. Neuroscience (2013), 12(231):420-431. https://doi.org/10.1016/j.neuroscience.2012.11.006

For complete list of publication see http://bit.ly/PTgooglescholar