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Indian Institute of Science Education and Research
Thiruvananthapuram

Dr Karthik Chandiran
ICMR -DHR Fellow (Biology)
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  1. Chandiran K, Cauley LS. The diverse effects of transforming growth factor – β and SMAD signaling pathways during the CTL response. Front Immunol. 2023
  2. Suarez-Ramirez JE, Cauley LS, Chandiran K. CTLs get SMAD when pathogens tell them where to go. J Immunol. 2022 (Corresponding Author)
  3. Chandiran K, Suarez-Ramirez JE, Hu Y, Jellison ER, Ugur Z, Low JS, McDonald B, Kaech SM, Cauley LS. SMAD4 and TGFβ are architects of inverse genetic programs during fate-determination of antiviral memory CD8 T cells. eLife. 2022.
  4. Russo AJ, Vasudevan SO, Méndez-Huergo SP, Kumari P, Menoret A, Duduskar S, Wang C, Pérez Sáez JM, Fettis MM, Li C, Liu R, Wanchoo A, Chandiran K, Ruan J, Vanaja SK, Bauer M, Sponholz C, Hudalla GA, Vella AT, Zhou B, Deshmukh SD, Rabinovich GA, Rathinam VA. Intracellular immune sensing promotes inflammation via gasdermin D-driven release of a lectin alarmin. Nat Immunol. 2021
  5. Suarez-Ramirez JE, Chandiran K, Brocke S, Cauley LS. Immunity to Respiratory Infection Is Reinforced Through Early Proliferation of Lymphoid TRM Cells and Prompt Arrival of Effector CD8 T Cells in the Lungs. Front Immunol. 2019
  6. Ozay EI, Vijayaraghavan J, Gonzalez-Perez G, Shanthalingam S, Sherman HL, Garrigan DT Jr, Chandiran K, Torres JA, Osborne BA, Tew GN, Slukvin II, Macdonald RA, Kelly K, Minter LM. Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease. Stem Cell Res. 2019
  7. Chandiran K, Lawlor R, Pannuti A, Gonzalez-Perez G, Srinivasan J, Golde TE, Miele L, Osborne BA, Minter LM. Notch1 primes CD4 T cells for T helper type I differentiation through its early effects on miR-29.  Mol Immunology. 2018
  8. Shin HM, Tilahun ME, Cho OH, Chandiran K, Kuksin CA, Keerthivasan S, Fauq AH, Golde TE, Miele L, Thome M, Osborne BA, Minter LM. Notch1 can initiate NF-κB activation via cytosolic interactions with components of the T cell signalosome. Front Immunol. 2014.
  9. Babu S, Bhat SQ, Pavan Kumar N, Lipira AB, Kumar S, Karthik C, Kumaraswami V, Nutman TB. Filarial lymphedema is characterized by antigen-specific Th1 and Th17 proinflammatory responses and a lack of regulatory cells. PLoS Negl Trop Dis. 2009