IISER TVM is a fully residential institute. Separate hostel accommodation is provided for boys and girls. Institute has currently two functional hostel buildings with 188-bedded in each block in the permanent campus:
Rooms in hostels are furnished with two single beds, common study table and Chairs. Common TV room in each Hall of residence and provides ample scope for recreations in the first floor of CDH.
A fully furnished central Dining hall to cater the dining needs of the students. It is supervised by student body called as students Mess Committee. Mess Committee has student representatives from all the batches & a Faculty coordinator. IISER TVM has students from all the regions of India. So Mess Committee focuses on fixing a menu which is best for people from all regions of India.
Medical center of Indian Institute of Science Education and Research, Thiruvananthapuram provides round the clock medical facility & fully equipped ambulance (Round the clock) to handle emergency cases. Medical facilities are given vital importance and each student is given complete care on admission itself. Medical insurance is given to each student so as to exclude financial problems and can get prime medical support. Referrals for specialty care are arranged with tie-up hospitals.