Indian Institute of Science Education and Research Thiruvananthapuram

IISER TVM Decennial Celebrations



Dr Mahesh Hariharan

Associate Professor

Email : bWFoZXNoQGlpc2VydHZtLmFjLmlu , Phone :  +91 (0)471 2778101

Web Link  : http://faculty.iisertvm.ac.in/hariharan




  1. Long Alkyl Side-Chains Impede Exciton Interaction in Organic Light Harvesting Crystals
    K. Nagarajan, G. Gopan, R. T. Cheriya and M. Hariharan*
    ChemComm, 2017, (In Press)
  2. Twisted Perylene Diimides with Tunable Redox Properties for Organic Sodium-Ion Batteries
    H. Banda; D. Damien; K. Nagarajan; A. Raj, M. Hariharan* and M. M. Shaijumon*
    Adv. Energy Mater. 2017, (In Press)
  3. Self-Assembled Donor-Acceptor Trefoils: Long-Lived Charge Separated State Through Aggregation
    A. R. Mallia and M. Hariharan*
    J. Phys. Chem. 2017, 121, 4778–4788
  4. Persistent Charge Separated States in Self-Assembled Twisted Non-Symmetric Donor-Acceptor Triad
    A. R. Mallia, A. M. Philip, V. Bhat and M. Hariharan*
    J. Phys. Chem. 2017, 121, 4765–4777 (Front Cover)
  5. Enhanced Intersystem Crossing in Core-Twisted Aromatics
    K. Nagarajan, A. R. Mallia, K. Muraleedharan and M. Hariharan*
    Chem. Sci., 2017, 8, 1776-1782 (Outside Back Cover)
  6. V-shaped Oxydiphthalimides: Side Chain Engineering Regulates Crystallisation-Induced Emission Enhancement
    G. Gopan, P. S. Salini, S. Deb and M. Hariharan*
    CrystEngComm 2017, 19, 419 (Front Cover)
  7. Crystalline Triphenylamine Substituted Arenes: Solid State Packing and Luminescence Properties
    A. R. Mallia, R. Ramakrishnan, M. A. Niyas, R. Sethy and M. Hariharan*
    CrystEngComm, 2017, 19, 817 - 825


  1. Prolonged Charge Separated States in Twisted Stacks of All-carbon Donor and Acceptor Chromophores
    A. M. Philip, A. R. Mallia and M. Hariharan*
    J. Phys. Chem. Lett. 2016, 7, 4751–4756 (ACS Liveslides)
  2. On the Origin of Multiexponential Fluorescence Decays from 2-Aminopurine-Labeled Dinucleotides
    J. Remington, A. Philip, M. Hariharan and B. Kohler*
    J. Chem. Phys. 2016, 145, 155101
  3. Columnar/Lamellar Packing in Cocrystals of Arylbipyridines with Diiodoperfluorobenzene
    R. Ramakrishnan, A. R. Mallia, M. A. Niyas, R. Sethy and M. Hariharan*

    Cryst. Growth Des. 2016, 10.1021/acs.cgd.6b00968.
    Link: http://pubs.acs.org/doi/abs/10.1021/acs.cgd.6b00968
  4. Haloacetylation Driven Transformation of Sandwich Herringbone to Lamellar/Columnar Packing in Pyrene
    P. S. Salini, S. K. Rajagopal and M. Hariharan*

    Cryst. Growth Des. 2016, 10.1021/acs.cgd.6b00919.
    Link: http://pubs.acs.org/doi/abs/10.1021/acs.cgd.6b00919
  5. S•••π, π−π and C−H•••π Contacts Regulate Solid State Fluorescence in Regioisomeric Bisthiazolylpyrenes
    S. K. Rajagopal, P. S. Salini and M. Hariharan*

    Cryst. Growth Des. 2016, 16, 4567–4573.
    Link: http://pubs.acs.org/doi/abs/10.1021/acs.cgd.6b00676
  6. Crystallization Induced Green-Yellow-Orange Emitters Based on Benzoylpyrenes
    S. K. Rajagopal, V. S. Reddy and M. Hariharan*

    CrystEngComm 2016, 18, 5089-5094 (Outside Frontispiece).
    Link: http://pubs.rsc.org/en/content/articlelanding/2016/CE/c6ce00610h#!divAbstract
  7. Access to Triplet Excited State in Core-Twisted Perylenediimide
    K. Nagarajan, A. R. Mallia, V. S. Reddy and M. Hariharan*

    J. Phys. Chem. C 2016, 120, 8443–8450.
    Link: http://pubs.acs.org/doi/abs/10.1021/acs.jpcc.6b00755
  8. Crystallization induced enhanced emission in conformational polymorphs of a rotationally flexible molecule
    A. R. Mallia, R. Sethy, V. Bhat and M. Hariharan*

    J. Mater. Chem. C 2016, 4, 2931-2935.
    Link: http://pubs.rsc.org/en/content/articlelanding/tc/2016/c5tc03188e#!divAbstract


  1. Nonparallel Stacks of Donor and Acceptor Chromophores Evade Geminate Charge Recombination
    A. R. Mallia, P. S. Salini and M. Hariharan*

    J. Am. Chem. Soc. 2015, 137, 15604–15607 (Front Cover and JACS Spotlights).
    Link: http://pubs.acs.org/doi/full/10.1021/jacs.5b08257
  2. A Polyimide based all-organic sodium ion battery
    H. Banda, D. Damien, K. Nagarajan, M. Hariharan and M. M. Shaijumon*

    J. Mater. Chem. A 2015, 3, 10453-10458.
    Link: http://pubs.rsc.org/en/content/articlelanding/2015/ta/c5ta02043c#!divAbstract


  1. C–H•••H–C and C–H•••π Contacts Aid Transformation of Dimeric to Monomeric Anthracene in the Solid State
    K. Nagarajan, S. K. Rajagopal and M. Hariharan*

    CrystEngComm 2014, 16, 8946-8949.
    Link: http://pubs.rsc.org/en/Content/ArticleLanding/2014/CE/C4CE01278J#!divAbstract
  2. Progressive Acylation of Pyrene Engineers Solid State Packing and Colour via C–H•••H–C, C–H•••O and π-π Interactions
    S. K. Rajagopal, A. M. Philip, K. Nagarajan and M. Hariharan*

    Chem. Commun. 2014, 50, 8644-8647 (Inside Front Cover).
    Link: http://pubs.rsc.org/en/Content/ArticleLanding/2014/CC/c4cc01897d#!divAbstract
  3. Light Harvesting Vesicular Donor-Acceptor Scaffold Limits the Rate of Charge Recombination in the Presence of an Electron Donor
    R. T. Cheriya, A. R. Mallia and M. Hariharan*

    Energy Environ. Sci. 2014, 7, 1661-1669 (Front Cover; Hot Article).
    Link: http://pubs.rsc.org/en/Content/ArticleLanding/2014/EE/c3ee43293a#!divAbstract
  4. Non-natural G-quadruplex in a Non-natural Environment
    S. K. Rajagopal and M. Hariharan*

    Photochem. Photobiol. Sci. 2014, 13, 157-161 (Nick Turro’s Special Issue).
    Link: http://pubs.rsc.org/en/Content/ArticleLanding/2014/PP/c3pp50199j#!divAbstract
  5. Thymine Photodimer Formation in DNA Hairpins. Unusual Conformations Favor (6-4) vs. (2+2) Adducts
    M. Hariharan,* K. Siegmund, C. Saurel, M. McCullagh, G. C. Schatz and F. D. Lewis*

    Photochem. Photobiol. Sci. 2014, 13, 266-271 (Nick Turro’s Special Issue).
    Link: http://pubs.rsc.org/en/Content/ArticleLanding/2014/PP/c3pp50283j#!divAbstract


  1. Thermal Response of DNA Supramolecular Polymers Assembled with Hydrophobic Sticky Ends
    M. Hariharan,* Y. Zheng, B. Rybtchinski and F. D. Lewis*

    J. Phys. Chem. B, 2013, 117, 14649–14654.
    Link: http://pubs.acs.org/doi/abs/10.1021/jp4087078
  2. Perylene Polyimide Based Organic Electrode Materials for Rechargeable Lithium Batteries
    P. Sharma, D. Damien, K. Nagarajan, M. M. Shaijumon,* and M. Hariharan*

    J. Phys. Chem. Lett., 2013, 4, 3192–3197 (One of the most read articles).
    Link: http://pubs.acs.org/doi/abs/10.1021/jz4017359
  3. Breakdown of Exciton Splitting through Electron Donor–Acceptor Interaction: A Caveat for the Application of Exciton Chirality Method in Macromolecules
    J. Joy, R. T. Cheriya, K. Nagarajan, A. Shaji, and M. Hariharan*

    J. Phys. Chem. C, 2013, 117, 17927–17939.
    Link: http://pubs.acs.org/doi/abs/10.1021/jp403431w
  4. Single Component Organic Light-Harvesting Red Luminescent Crystal
    R. T. Cheriya, K. Nagarajan and M. Hariharan*

    J. Phys. Chem. C, 2013, 117, 3240-3248.
    Link: http://pubs.acs.org/doi/abs/10.1021/jp309752x


  1. DNA-Enforced Conformational Restriction of an Atropisomer
    R. T. Cheriya, J. Joy, S. K. Rajagopal, K. Nagarajan and M. Hariharan*

    J. Phys. Chem. C, 2012, 116, 22631-22636.
    Link: http://pubs.acs.org/doi/abs/10.1021/jp308260a
  2. Effect of Temperature on Symmetry Breaking Excited State Charge Separation: Restoration of Symmetry at Elevated Temperature
    H. Khandelwal, A. R. Mallia, R. T. Cheriya and M. Hariharan*

    Phys. Chem. Chem. Phys., 2012, 15282-15285.
    Link: http://pubs.rsc.org/en/content/articlelanding/2012/cp/c2cp42452e#!divAbstract
  3. Energy Transfer in Near-Orthogonally Arranged Chromophores Separated through a Single Bond
    R. T. Cheriya, J. Joy, A. P. Alex, A. Shaji, and M. Hariharan*

    J. Phys. Chem. C, 2012, 116, 12489–12498.
    Link: http://pubs.acs.org/doi/abs/10.1021/jp303406p
  4. Facially-Selective Thymine-Thymine Photodimerization in TTT Triads
    P. P. Neelakandan, Z. Pan, M. Hariharan and F. D. Lewis*

    Photochem. Photobiol. Sci., 2012, 11, 889-892.
    Link: http://pubs.rsc.org/en/content/articlelanding/2012/pp/c2pp25089f#!divAbstract


  1. Electron Donor–Acceptor Interactions with Flanking Purines Influence the Efficiency of Thymine Photodimerization
    Z. Pan, M. Hariharan, J. D. Arkin, A. S. Jalilov, M. McCullagh, G. C. Schatz, and F. D. Lewis*

    J. Am. Chem. Soc. 2011, 133, 20793–20798.
    Link: http://pubs.acs.org/doi/abs/10.1021/ja205460f
  2. Conformation of a Dodecane DNA Hairpin Linker. Multiple Gauche Bonds Cover the Bases
    K. Siegmund, M. Hariharan, and F. D. Lewis*

    J. Phys. Chem. B, 2011, 115, 3740–3746.
    Link: http://pubs.acs.org/doi/abs/10.1021/jp201188f


  1. Hydrophobic Self-Assembly of a Perylenediimide-Linked DNA Dumbbell into Supramolecular Polymers
    P. Neelakandan, Z. Pan, M. Hariharan, Y. Zheng, F. D. Lewis*, H. Weissman, and B. Rybtchinski*

    J. Am. Chem. Soc. 2010, 132, 15808-15813.
    Link: http://pubs.acs.org/doi/abs/10.1021/ja1076525
  2. Conformational Control of Thymine Photodimerization in Single-Strand and Duplex DNA Containing Locked Nucleic Acid TT Steps
    M. Hariharan, M. McCullagh, G. C. Schatz, and F. D. Lewis*

    J. Am. Chem. Soc. 2010, 132, 12856-12858.
    Link: http://pubs.acs.org/doi/abs/10.1021/ja106203q
  3. Structure and Stability of Alkane-Linked DNA Hairpin Conjugates
    M. Hariharan,* K. Siegmund, and F. D. Lewis*

    J. Org. Chem. 2010, 75, 6236–6243.
    Link: http://pubs.acs.org/doi/abs/10.1021/jo1013299
  4. Perylenediimide-Linked DNA Dumbbells: Long-Distance Electronic Interactions and Hydrophobic Assistance of Base-Pair Melting
    M. Hariharan, K. Siegmund, Y. Zheng, H. Long, G. C. Schatz, and F. D. Lewis*

    J. Phys. Chem. C 2010, 114, 20466–20471.
    Link: http://pubs.acs.org/doi/abs/10.1021/jp1048309
  5. DNA Base-Pair Flipping with Fluorescent Perylenediimide Pincers
    T. A. Zeidan, M. Hariharan, K. Siegmund, and F. D. Lewis*

    Photochem. Photobiol. Sci. 2010, 9, 916-922.
    Link: http://pubs.rsc.org/en/content/articlelanding/2010/pp/c0pp00044b#!divAbstract
  6. Conformational Control of TT-Dimerization in DNA Hairpins. A Molecular Dynamics Study
    M. McCullagh, M. Hariharan, F. D. Lewis*, D. Markovitsi, T. Douki and G. C. Schatz*

    J. Phys. Chem. B 2010, 114, 5215-5221.
    Link: http://pubs.acs.org/doi/abs/10.1021/jp100983t
  7. Site-selective Interactions: Squaraine Dye-Serum Albumin Complexes with Enhanced Fluorescence and Triplet Yields
    V. S. Jisha, K. T. Arun, M. Hariharan and D. Ramaiah*

    J. Phys. Chem. B 2010, 114, 5912-5919.
    Link: http://pubs.acs.org/doi/abs/10.1021/jp100369x
  8. Electron Hopping among Cofacially Stacked Perylenediimides Assembled Using DNA Hairpins
    T. M. Wilson, T. A. Zeidan, M. Hariharan, F. D. Lewis*, and M. R. Wasielewski*

    Angew. Chem. 2010, 49, 2385-2388.
    Link: http://onlinelibrary.wiley.com/wol1/doi/10.1002/anie.200907339/abstract
  9. Direct Evidence on the External Stimuli Induced Dissembly of DNA through Microscopic Techniques
    M. Hariharan, E. Kuruvilla and D. Ramaiah*

    J. Phys. Chem. Lett. 2010, 1, 834-838.
    Link: http://pubs.acs.org/doi/10.1021/jz900447p
  10. Photoinduced DNA Damage Efficiency and Cytotoxicity of Novel Viologen Linked Pyrene Conjugates
    M. Hariharan, D. Ramaiah*, I. Schulz, S. C. Karunakaran and B. Epe

    Chem. Comm. 2010, 46, 2064-2066.
    Link: http://pubs.rsc.org/en/Content/ArticleLanding/2010/CC/b924943e#!divAbstract


  1. Hydrophobic Dimerization and Thermal Dissociation of Perylenediimide-Linked DNA Hairpins
    M. Hariharan, Y. Zheng, H. Long, T. A. Zeidan, G. C. Schatz, J. Vura-Weis, M. R. Wasielewski, X. Zuo, D. M. Tiede, and F.. D. Lewis*

    J. Am. Chem. Soc. 2009, 131, 5920-5929.
    Link: http://pubs.acs.org/doi/abs/10.1021/ja900347t
  2. Sum rules and determination of exciton coupling using absorption and circular dichroism spectra of biological polymers
    A. Burin, M. Armbruster, M. Hariharan and F. D. Lewis*
    Proc. Natl. Acad. Sci. USA 2009, 106, 989-984.
    Link: http://www.pnas.org/content/106/4/989


  1. Photoinduced Charge Separation in Pyrenedicarboxamide-linked DNA Hairpins,
    P. Daublain, K. Siegmund, M. Hariharan, J. Vura-Weis, M. R. Wasielewski, F. D. Lewis*, V. Shafirovich*, Q. Wang, M. Raytchev, and Torsten Fiebig*

    Photochem. Photobiol. Sci. 2008, 7, 1501-1508.
    Link: http://pubs.rsc.org/en/content/articlelanding/2008/pp/b813995d#!divAbstract
  2. Context-Dependent Photodimerization in Isolated Thymine-Thymine Steps in DNA,
    M. Hariharan and F. D. Lewis*

    J. Am. Chem. Soc. 2008, 130, 11870-11871.
    Link: http://pubs.acs.org/doi/abs/10.1021/ja804950j


  1. Encapsulation of Electron Donor-Acceptor Dyads in b-Cyclodextrin Cavity: Unusual Planarization and Enhancement in Rate of Electron Transfer Reaction
    M. Hariharan, P. P. Neelakandan and D. Ramaiah*
    J. Phys. Chem. B, 2007, 111, 11940-11947.
    Link: http://pubs.acs.org/doi/abs/10.1021/jp074643d
  2. Chiral supramolecular assemblies of a squaraine dye in solution and thin films: concentration-, temperature-, and solvent-induced chirality inversion
    K. Jyothish, M. Hariharan and D. Ramaiah*
    Chem. Eur. J. 2007, 13, 5944-5951.
    Link: http://onlinelibrary.wiley.com/wol1/doi/10.1002/chem.200700130/abstract
  3. Selective Recognition of Tryptophan through the Inhibition of Intramolecular Charge-Transfer Interactions in an Aqueous Medium
    M. Hariharan, C. K. Suneesh and D. Ramaiah*

    Org. Lett. 2007, 9, 417-420.
    Link: http://pubs.acs.org/doi/abs/10.1021/ol062636m


  1. Novel Bifunctional Viologen-Linked Pyrene Conjugates: Synthesis and Study of their Interactions with Nucleosides and DNA
    M. Hariharan, J. Joseph and D. Ramaiah*
    J. Phys. Chem. B 2006, 110, 24678-24686.
    Link: http://pubs.acs.org/doi/abs/10.1021/jp063079o
  2. A Supramolecular ON-OFF-ON Fluorescence Assay for Selective Recognition of GTP
    P. P. Neelakandan, M. Hariharan and D. Ramaiah*

    J. Am. Chem. Soc. 2006, 128, 11334-11335.
    Link: http://pubs.acs.org/doi/abs/10.1021/ja062651m
  3. Site-Selective Binding and Dual Mode Recognition of Serum Albumin by a Squaraine Dye
    V. S. Jisha, K. T. Arun, M. Hariharan and D. Ramaiah*

    J. Am. Chem. Soc. 2006, 128, 6024-6025.
    Link: http://pubs.acs.org/doi/abs/10.1021/ja061301x


  1. Synthesis of a Novel Cyclic Donor-Acceptor Conjugate for Selective Recognition of ATP
    P. P. Neelakandan, M. Hariharan and D. Ramaiah*

    Org. Lett. 2005, 5765-5768.
    Link: http://pubs.acs.org/doi/abs/10.1021/ol052246k


  1. A Novel Cyclic Donor- Acceptor Conjugate, Process and a Supramolecular Fluorescent Marker Thereof
    D. Ramaiah, P. P. Neelakandan and M. Hariharan
    IN Patent No. 253901, dated August 31, 2012.